Practice question · Put in order
Arrange these levels of DNA packing from least to most condensed.
- Looped domains on a protein scaffold
- The fully condensed mitotic chromosome
- The 30 nm chromatin fibre
- Naked DNA double helix
- Nucleosomes, the beads-on-a-string arrangement
Hints
- Each level builds on the one below it.
- The most condensed state occurs only during cell division.
Show the answer
- Naked DNA double helix
- Nucleosomes, the beads-on-a-string arrangement
- The 30 nm chromatin fibre
- Looped domains on a protein scaffold
- The fully condensed mitotic chromosome
Why
Packing is hierarchical, with each level built from the one below. The whole hierarchy is reversible, because a permanently packed genome would be a permanently silent one.
Practise The Cell Nucleus
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