Practice question · True or false
Blocking the reuptake of serotonin will tend to DECREASE serotonin's effect on the receiving neuron.
Hints
- What does reuptake do?
- It clears transmitter out of the cleft.
Show the answer
False
Why
False. Reuptake removes serotonin from the synaptic cleft, so blocking it leaves the transmitter there longer and increases its effect, which is exactly how SSRIs work. The puzzle the mechanism does not explain is why the receptor change is immediate and the clinical benefit takes weeks.
Practise Synaptic Transmission
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More questions on Synaptic Transmission
- A regular opioid user needs steadily larger doses for the same effect, and feels terrible without any. What…
- An agonist and an antagonist can both bind the same receptor with equal affinity. What distinguishes them,…
- Select every statement that is TRUE about synaptic transmission.
- Order the events of chemical synaptic transmission.
- The action potential does not jump across the synaptic cleft. What crosses instead?
- Sort each drug action as an agonist or an antagonist.