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Principles of Laboratory Practice

Calibration and Systematic Errors

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Calibration links an instrument's reading to a known standard. Without it, all measurements may be systematically shifted.

Types of systematic error

ErrorDescriptionExample
Zero offsetInstrument doesn't read zero at zero inputScale reads 0.3g0.3 g with nothing on it
Scale factorReadings are consistently too high/lowRuler expanded by heat
Non-linearityError varies across the rangeSpring beyond Hooke's law
HysteresisReading depends on direction of changeMechanical backlash

Calibration procedure

  1. Measure a set of known standards spanning your range.
  2. Plot measured vs. true values.
  3. Fit a calibration curve (ideally linear: y=mx+by = mx + b).
  4. Use the inverse to correct all future readings.

Detecting systematic errors

Accuracy vs. precision

Tip: Systematic errors do not decrease with more measurements. The only cure is to identify and remove the source.
Common pitfall: Averaging cures only random error. A miscalibrated instrument delivers beautifully repeatable wrong numbers — precision without accuracy. Calibration against a known standard is the only cure for systematic bias.
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Principles of Laboratory Practice