Biology I / What Is Life? The Chemistry of Living Things
Practice question · Multiple choice

Why do phospholipids form a bilayer spontaneously when placed in water?

Hints
  1. Consider what each end of the molecule does in contact with water.
  2. A hydrophilic head and hydrophobic tails cannot both be satisfied unless the tails hide from water.
Show the answer

C. They are amphipathic, so water excludes the tails while accepting the heads

Why

A phospholipid has a water-loving head and water-fearing tails, so the only arrangement satisfying both is a sheet with tails buried inside. Water does the organising by exclusion, no machinery is needed, which is why membranes could arise before any protein existed to build them.

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