Practice question · Multiple choice
Ionotropic receptors act in milliseconds and metabotropic ones over seconds. Why does the second messenger cost so much time?
Hints
- Count the steps between binding and a change in membrane potential for each.
- One is a channel; the other triggers a chain.
Show the answer
B. Because metabotropic runs through a G-protein cascade first
Why
Steps cost time, and buy amplification and duration. Fast signalling is ionotropic; modulation that must outlast the signal is metabotropic.
Practise Synaptic Transmission
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